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Preventive therapy should be considered in patients having four or more headaches a month or at least eight headache days a month significantly debilitating attacks despite appropriate acute management difficulty tolerating or having a contraindication to acute therapy medication overuse headache patient preference.
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EFFECTIVE Divalproex Depakote metoprolol propranolol timolol topiramate Topamax and valproate Depacon are effective and should be offered for migraine prevention Frovatriptan Frova should be offered for short-term prevention of menstrual-associated migraine.
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